April 8, Cushing's Disease Awareness Day, is organized to celebrate the birthday of Dr. Harvey Cushing, a famous neurosurgeon who was the first to describe the condition in 1912. Firstly, Cushing's disease is one cause of Cushing's syndrome and shouldn't be confused. The disease is a rare and progressive disorder that occurs when a noncancerous tumor on the pituitary gland makes too much cortisol - the hormone associated with stress. It is the most common form of Cushing syndrome, making up about 70% of cases. Symptoms may include emotional disturbances, irritability, hypertension, purple striae, obesity, osteoporosis, red and round face, and more. However, it is often misdiagnosed, which is problematic as the condition worsens without treatment.